Coverage & Support

Only ZENPEP offers your patients MORE support

Looking for Coverage & Support for EPI patients with CF?
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ZENPEP is covered for
94% of patients with
commercial insurance and Medicare Part D1

ZENPEP is covered for 94% of
patients with commercial
insurance and Medicare Part D1

And 85% of those patients have no prior
authorization or step edit requirements2

  • MEDICARE and MEDICAID are properties of the US Department of Health and Human Services (DHHS) and the Centers for Medicare & Medicaid Services (CMS). No endorsement of any brand or product by the DHHS and/or CMS is implied or intended.
  • Data are not a guarantee of coverage, or partial or full payment, by any payers listed. Actual benefits determined by respective plan administrators. Insurer plans, coverage criteria, and formularies are subject to change without notice. Check each patient's coverage with applicable insurer. Nestle Health Science does not endorse any individual plans. Formulary coverage does not imply efficacy or safety.

302 MILLION INDIVIDUALS

302 MILLION
INDIVIDUALS

ZENPEP is covered for 302 million individuals with
commercial and Medicare channels/insurance, 10
million MORE individuals than Creon® (pancrelipase),
making it the most widely covered PERT available1*†

  • Creon is a registered trademark of AbbVie Products LLC.
  • *Products are not substitutable. Material differences exist between products. Consult each individual product's United States Prescribing Information for full details.
  • PERT=pancreatic enzyme replacement therapy.
  • †Analysis of MMIT coverage data For ZENPEP and Creon includes commercial, Medicare, Medicaid, and health insurance exchange lives with coverage status of "covered" or better. Coverage data are based on publicly available plan-level data and may not reflect individual patient eligibility.

ZENPEP is $0 for eligible commercially insured patients through Z-Save®‡

Z-Save gives your patients MORE savings with $0 for
each prescription and refill for eligible commercially
insured patients‡

Free Pure Encapsulations® vitamins and BOOST® supplements are mailed to Z-Save enrolled patients, subject to terms and conditions§||

  • ‡This offer is valid only for ZENPEP prescriptions through the Z-Save program. Check with pharmacist for copay discount. Maximum savings limit applies; patient out-of-pocket expense may vary. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. Please see non-CF Patient Support Program Terms, Conditions, and Eligibility Criteria at www.ZENPEPsupport.com.
  • §These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
  • ||Vitamins should be taken as directed on label or otherwise directed by a physician. Actual product, packaging, and materials may vary and are subject to substitution or replacement at any time.
  • Always read labels, warnings, and directions before using or consuming a product.
  • CF=cystic fibrosis.

Nestlé Health Science
is committed to help
your patients along
their treatment
journey

Nestlé Health Science is committed to help your patients
along their treatment journey

Nestlé Health Science supplements the care you’re giving your patients with educational information on EPI and PERT to help keep them on track with their treatment.

  • EPI=exocrine pancreatic insufficiency.

Only ZENPEP offers
the GoodStart™
Program, which gives patients
access to:

  • Pleio GoodStart™ is a trademark of Pleio, Inc.

Up to 5 FREE calls

An experienced GoodStart member will connect with your patient on adherence, education, and encouragement

Supportive messaging

21 days of supportive messaging from the GoodStart Minute by text or email

Additional resources

Patients get access to a brochure with helpful information, FAQs, savings, and more

Video Thumbnail

Patient video

Hear Dee’s personal struggle with
more than 30 years of undiagnosed
EPI symptoms

Watch the video
Discover how ZENPEP works
Get ZENPEP insurance coverage information

References: 1. MMIT Data on File. Nestle Health Science. Accessed March 2026. 2. ZENPEP Coverage, All Channels, MMIT Data on File. Nestlé Health Science. Accessed 2023.